MOLECULAR NEUROSURGERY WITH TARGETED TOXINS

Edited by RONALD G. WILEY, MD, PhD Departments of Neurology and Pharmacology,
Vanderbilt University School of Medicine
Douglas A. Lappi, PhD
Advanced Targeting Systems, San Diego, CA
The use of targeted cytotoxins in experimental neurobiology is a new field. This strategy involves producing highly selective neural lesions by targeting a cytotoxin into specific neurons based on their binding to surface membrane targets, such as neurotransmitter or growth factor receptors.The expression of surface membrane molecules correlates with the function of specific types of neurons."Molecular Neurosurgery with Targeted Toxins" seeks to provide a selected collection of examples of this approach that have been implemented with great success.
2005
http://rapidshare.com/files/170030668/Molecular_Neurosurgery_With_Targeted_Toxins.pdf